tdbR00001097

Name	Value
Coding AA:	Sec
Anticodon sequence:	1CA
Organism:	Homo sapiens NCBI:txid9606
RNA type:	cytoplasmic
Sequence:	GCCCGGAUGAUCCUCAGUGGUCUGGGGUGCAGGCU1CAЧACCUGUAGCUGUCUAGCGACAGAGUGGUPCAѢUUCCACCUUUCGGGCGCCA
Unmodified sequence:	GCCCGGAUGAUCCUCAGUGGUCUGGGGUGCAGGCUUCAAACCUGUAGCUGUCUAGCGACAGAGUGGUUCAAUUCCACCUUUCGGGCGCCA
Secondary structure:	(((((((((..((((((....))))))((((((.......))))))((((((....))))))((((.......)))))))))))))....
Prepared by:	Database creators
Version:	3 (June 29, 2026), created: June 29, 2026, modified: Aug. 11, 2026
Folding free energy [kcal/mol]:	-40.10
Pre-aligned sequence: Pre-aligned secondary structure:	GCCCGGAUGAUCCUCAG--UGG-UCUGGGGUGCAGGCU1CAЧACCUGUAGCUG--UCUA---GCGAC-AGAGUGGUPCAѢUUCCACCUUUCGGGCGCCA (((((((((..((((((.......))))))((((((.......))))))((((..((.......))).)))((((.......)))))))))))))....
Variants & Diseases:	C65G, Sec-TCA, Euthyroid hyperthyroxinemia; selenium deficiency (only homozygous mutations)
Publications:	Regulation of A-to-I RNA editing and stop codon recoding to control selenoprotein expression during skeletal myogenesis. Yuta Noda, Shunpei Okada, Tsutomu Suzuki Nature communications volume: 13 issue: 1 date: May 6, 2022 epub: May 6, 2022 PUBMED ID: 35523818 DOI: 2503
Comments:	mcm5U34 can also be an mcm5Um34, depending on the Se availability and its level differed