| Coding AA: | Gln | 
            
                | Anticodon sequence: | CUG | 
            
                | Organism: | Escherichia coli
                    
                        NCBI:txid562 | 
            
                | RNA type: | cytoplasmic | 
            
                | Sequence: | UGGGGUA4CGCCAAGC#GDAAGGCACCGGAJUCUG/PPCCGGCAUUCCGAGGTPCGAAUCCUCGUACCCCAGCCA | 
            
                | Unmodified sequence: | UGGGGUAUCGCCAAGCGGUAAGGCACCGGAUUCUGAUUCCGGCAUUCCGAGGUUCGAAUCCUCGUACCCCAGCCA | 
            
                | Secondary structure: | (((((((..(((.........))).(((((.......))))).....(((((.......)))))))))))).... | 
            
                
                    | PDB ID: | 1o0c, 1qrs, 1qrt, 1qru, 1qtq, 1zjw, 2re8, 4jxx, 4jxz, 4jyz | 
            
            
                | Homology model or structure extracted from PDB:
 | Extracted
                         Download
                    
                    (last update Sept. 6, 2019) | 
            
                | Prepared by: | Database creators | 
            
                | Version: | 1 (Sept. 6, 2019), created: Feb. 25, 2019, modified: July 1, 2025 | 
            
                
                    | Folding free energy [kcal/mol]: | -28.00 | 
            
            
                
                    | Pre-aligned sequence: Pre-aligned secondary structure:
 | -UGGGGUA4CGCCAAGC--#GD--AAGGCACCGGAJUCUG/PPCCGGCA-------------------UUCCGAGGTPCGAAUCCUCGUACCCCAGCCA .(((((((..(((.............))).(((((.......)))))........................(((((.......))))))))))))....
 | 
            
            
                
                    | Publications: | 
                        
                            The nucleotide sequences of the two glutamine transfer ribonucleic acids from Escherichia coli.M Yaniv, W R Folk
 The Journal of biological chemistry
 volume: 250
                                issue: 9
                                date: May 10, 1975
                                
                                PUBMED ID: 164464
Amino acid discrimination by a class I aminoacyl-tRNA synthetase specified by negative determinants.Timothy L Bullock, Nathan Uter, T Amar Nissan, John J Perona
 Journal of molecular biology
 volume: 328
                                issue: 2
                                date: April 25, 2003
                                
                                PUBMED ID: 12691748
Crystal structures of three misacylating mutants of Escherichia coli glutaminyl-tRNA synthetase complexed with tRNA(Gln) and ATP.J G Arnez, T A Steitz
 Biochemistry
 volume: 35
                                issue: 47
                                date: Nov. 26, 1996
                                
                                PUBMED ID: 8942633
How glutaminyl-tRNA synthetase selects glutamine.V L Rath, L F Silvian, B Beijer, B S Sproat, T A Steitz
 Structure (London, England : 1993)
 volume: 6
                                issue: 4
                                date: April 15, 1998
                                
                                PUBMED ID: 9562563
tRNA-dependent aminoacyl-adenylate hydrolysis by a nonediting class I aminoacyl-tRNA synthetase.Ita Gruic-Sovulj, Nathan Uter, Timothy Bullock, John J Perona
 The Journal of biological chemistry
 volume: 280
                                issue: 25
                                date: June 24, 2005
                                epub: April 20, 2005
                                PUBMED ID: 15845536
A rationally engineered misacylating aminoacyl-tRNA synthetase.Timothy L Bullock, Annia RodrÃguez-Hernández, Eleonora M Corigliano, John J Perona
 Proceedings of the National Academy of Sciences of the United States of America
 volume: 105
                                issue: 21
                                date: May 27, 2008
                                epub: May 13, 2008
                                PUBMED ID: 18477696
                                DOI: 10.1073/pnas.0711812105
Structural and mechanistic basis for enhanced translational efficiency by 2-thiouridine at the tRNA anticodon wobble position.Annia Rodriguez-Hernandez, Jessica L Spears, Kirk W Gaston, Patrick A Limbach, Howard Gamper, Ya-Ming Hou, Rob Kaiser, Paul F Agris, John J Perona
 Journal of molecular biology
 volume: 425
                                issue: 20
                                date: Oct. 23, 2013
                                epub: May 28, 2013
                                PUBMED ID: 23727144
                                DOI: 10.1016/j.jmb.2013.05.018
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