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tdbR00000276

NameValue
Coding AA: Met
Anticodon sequence: MAU
Organism: Escherichia coli NCBI:txid562
RNA type: cytoplasmic
Sequence: GGCUACG4AGCUCAGDD#GDDAGAGCACAUCACUMAU6APGAUGGG7XCACAGGTPCGAAUCCCGUCGUAGCCACCA
Unmodified sequence: GGCUACGUAGCUCAGUUGGUUAGAGCACAUCACUCAUAAUGAUGGGGUCACAGGUUCGAAUCCCGUCGUAGCCACCA
Secondary structure: (((((((..((((.........)))).(((((.......))))).....((.((.......)).)))))))))....
Homology model or
structure extracted from PDB:
Model Download (by Moderna) Download (by RNA Composer) (last update July 2, 2025)
Prepared by: Database creators
Version: 1 (Sept. 6, 2019), created: Feb. 25, 2019, modified: June 29, 2026
Folding free energy [kcal/mol]: -20.00
Pre-aligned sequence:
Pre-aligned secondary structure:
-GGCUACG4AGCUCAGDD-#GDD-AGAGCACAUCACUMAU6APGAUGGG-------------------7XCACAGGTPCGAAUCCCGUCGUAGCCACCA
.(((((((..((((...........)))).(((((.......)))))........................((.((.......)).)))))))))....
Publications:
  • The nucleotide sequence of methionine transfer RNA-M.
    S Cory, K A Marcker
    European journal of biochemistry
    volume: 12 issue: 1 PUBMED ID: 4313980
Comments: 16 PARTIALLY U ; 18 PARTIALLY G

Aminoacylation

NameValue
Positive identity elements regulating aminoacylation: A73; C34; A35; U36; initiator-specific elements include C32, U33, A37 and acceptor-stem features in some assays
Negative identity elements antideterminants of aminoacylation: NA
Citation: Pak,M., Pallanck,L. and Schulman,L.H. (1992) Conversion of a methionine initiator tRNA into a tryptophan-inserting elongator tRNA in vivo. Biochemistry, 31, 3303–3309.
DOI: 10.1021/bi00128a001
PMID: 1554714

Secondary structure

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Tertiary structure

Model based on:
Moderna
RNA Composer