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tdbR00000369

NameValue
Coding AA: Arg
Anticodon sequence: ICG
Organism: Saccharomyces cerevisiae NCBI:txid4932
RNA type: cytoplasmic
Sequence: PUCCUCGUKLCCCAADGGDCACGGCRPCUGGCUICGAACCAGAAGADU?CAGGTPCA"GUCCUGGCGGGGAAGCCA
Unmodified sequence: UUCCUCGUGGCCCAAUGGUCACGGCGUCUGGCUACGAACCAGAAGAUUCCAGGUUCAAGUCCUGGCGGGGAAGCCA
Secondary structure: (((((((..(((..........))).(((((.......))))).....(((((.......))))))))))))....
Homology model or
structure extracted from PDB:
Model Download (by Moderna) Download (by RNA Composer) (last update July 2, 2025)
Prepared by: Database creators
Version: 1 (Sept. 6, 2019), created: Feb. 25, 2019, modified: June 29, 2026
Folding free energy [kcal/mol]: -23.40
Pre-aligned sequence:
Pre-aligned secondary structure:
-PUCCUCGUKLCCCAAD--GGDC-ACGGCRPCUGGCUICGAACCAGAAG-------------------ADU?CAGGTPCA"GUCCUGGCGGGGAAGCCA
.(((((((..(((.............))).(((((.......)))))........................(((((.......))))))))))))....
Publications:
  • The primary structure of tRNAIIAgr from brewers' yeast. 2. Partial digestion with ribonuclease T1 and derivation of the complete sequence.
    J Weissenbach, R Martin, G Dirheimer
    European journal of biochemistry
    volume: 56 issue: 2 date: Aug. 15, 1975 PUBMED ID: 1100396

Aminoacylation

NameValue
Positive identity elements regulating aminoacylation: C35 plus G36/U36 combinations; U20/C20a/U20a context; A38 in some isoacceptors
Negative identity elements antideterminants of aminoacylation: Asp identity can be cryptic in yeast tRNAArg; mutations C38 and G73 switch minor tRNA4Arg(CCG) toward Asp acceptance.
Citation: Liu,W., Huang,Y., Eriani,G., Gangloff,J., Wang,E.-D. and Wang,Y.-L. (1999) A single base substitution in the variable pocket of yeast tRNAArg eliminates species-specific aminoacylation. Biochim. Biophys. Acta, 1473, 356–362.
DOI: 10.1016/s0304-4165(99)00143-9
PMID: 10594373

Secondary structure

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Tertiary structure

Model based on:
Moderna
RNA Composer