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tdbR00000494

NameValue
Coding AA: Trp
Anticodon sequence: BCA
Organism: Saccharomyces cerevisiae NCBI:txid4932
RNA type: cytoplasmic
Sequence: GAAGCGGUKLCUCAAD#GDAGAGCPPPCGABUBCAAAPCGAAGG7DUGCAGGTPCA"UUCCUGPCCGUUUCACCA
Unmodified sequence: GAAGCGGUGGCUCAAUGGUAGAGCUUUCGACUCCAAAUCGAAGGGUUGCAGGUUCAAUUCCUGUCCGUUUCACCA
Secondary structure: (((((((..((((.......))))((((((.......))))))....(((((.......))))))))))))....
Homology model or
structure extracted from PDB:
Model Download (by Moderna) Download (by RNA Composer) (last update July 2, 2025)
Prepared by: Database creators
Version: 1 (Sept. 6, 2019), created: Feb. 25, 2019, modified: June 29, 2026
Folding free energy [kcal/mol]: -22.10
Pre-aligned sequence:
Pre-aligned secondary structure:
-GAAGCGGUKLCUCAAD--#GD--AGAGCPPPCGABUBCAAAPCGAAGG-------------------7DUGCAGGTPCA"UUCCUGPCCGUUUCACCA
.(((((((..((((...........))))((((((.......)))))).......................(((((.......))))))))))))....
Publications:
  • The primary structure of tryptophan transfer ribonucleic acid from brewer's yeast. II. Partial digestion with pancreatic ribonuclease and derivation of complete sequence.
    G Keith, A Roy, J P Ebel, G Dirheimer
    Biochimie
    volume: 54 issue: 11 PUBMED ID: 4350483
Comments: 65 PARTIALLY U

Aminoacylation

NameValue
Positive identity elements regulating aminoacylation: A73; G1-C72; U5-G68/G5-C68 context; C34; C35; A36
Negative identity elements antideterminants of aminoacylation: NA
Citation: Yesland,K.D. and Johnson,J.D. (1993) Anticodon bases C34 and C35 are major, positive, identity elements in Saccharomyces cerevisiae tRNATrp. Nucleic Acids Res., 21, 5079–5084.
DOI: 10.1093/nar/21.22.5079
PMID: 8255761

Secondary structure

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Tertiary structure

Model based on:
Moderna
RNA Composer