tdbR00000066

Name	Value
Coding AA:	Phe
Anticodon sequence:	GAA
Organism:	Thermus thermophilus NCBI:txid274
RNA type:	cytoplasmic
Sequence:	GCCGALG4AGCUCAGUU#GDAGAGCAUGCGACUGAA+APCGCAGU7UCGGCGGTPCG"UUCCGCUCCUCGGCACCA
Unmodified sequence:	GCCGAGGUAGCUCAGUUGGUAGAGCAUGCGACUGAAAAUCGCAGUGUCGGCGGUUCGAUUCCGCUCCUCGGCACCA
Secondary structure:	(((((((..((((........)))).(((((.......))))).....(((((.......))))))))))))....
PDB ID:	3tup, 1eiy, 3b0v
Homology model or structure extracted from PDB:	Extracted Download (last update Sept. 6, 2019)
Prepared by:	Database creators
Version:	1 (Sept. 6, 2019), created: Feb. 25, 2019, modified: Sept. 23, 2019
Folding free energy [kcal/mol]:	-30.60
Pre-aligned sequence: Pre-aligned secondary structure:	-GCCGALG4AGCUCAGUU-#GD--AGAGCAUGCGACUGAA+APCGCAGU-------------------7UCGGCGGTPCGAUUCCGCUCCUCGGCACCA .(((((((..((((...........)))).(((((.......)))))........................(((((.......))))))))))))....
Publications:	Sequence and base modifications of two phenylalanine-tRNAs from Thermus thermophilus HB8. U Grawunder, A Schön, M Sprinzl Nucleic acids research volume: 20 issue: 1 date: Jan. 11, 1992 PUBMED ID: 1738592 Crystal structure of human mitochondrial PheRS complexed with tRNA(Phe) in the active "open" state. Liron Klipcan, Nina Moor, Igal Finarov, Naama Kessler, Maria Sukhanova, Mark G Safro Journal of molecular biology volume: 415 issue: 3 date: Jan. 20, 2012 epub: Nov. 23, 2011 PUBMED ID: 22137894 DOI: 10.1016/j.jmb.2011.11.029 The crystal structure of phenylalanyl-tRNA synthetase from thermus thermophilus complexed with cognate tRNAPhe. Y Goldgur, L Mosyak, L Reshetnikova, V Ankilova, O Lavrik, S Khodyreva, M Safro Structure (London, England : 1993) volume: 5 issue: 1 date: Jan. 15, 1997 PUBMED ID: 9016717 Molecular basis of dihydrouridine formation on tRNA. Futao Yu, Yoshikazu Tanaka, Keitaro Yamashita, Takeo Suzuki, Akiyoshi Nakamura, Nagisa Hirano, Tsutomu Suzuki, Min Yao, Isao Tanaka Proceedings of the National Academy of Sciences of the United States of America volume: 108 issue: 49 date: Dec. 6, 2011 epub: Nov. 28, 2011 PUBMED ID: 22123979 DOI: 10.1073/pnas.1112352108 N7-Methylguanine at position 46 (m7G46) in tRNA from Thermus thermophilus is required for cell viability at high temperatures through a tRNA modification network. Chie Tomikawa, Takashi Yokogawa, Tamotsu Kanai, Hiroyuki Hori Nucleic acids research volume: 38 issue: 3 epub: Nov. 24, 2009 PUBMED ID: 19934251 DOI: 10.1093/nar/gkp1059
Comments:	8 DEGREE OF MODIFIKATION IS 60 PERCENT; 54 DEGREE OF MODIFIKATION TO P IS 10 PERCENT; 37 + ALSO *