tdbR00000674
| Name | Value |
|---|---|
| Coding AA: | Phe |
| Anticodon sequence: | GAA |
| Organism: | Homo sapiens NCBI:txid9606 |
| RNA type: | cytoplasmic |
| Sequence: | GCCGA;AUAGCUCAGUUGGGAGAGCGUUAGACUGAAGAUCUAAAGGNCCCUGGUUCHAUCCCGGGUUUCGGCACCA |
| Unmodified sequence: | GCCGAGAUAGCUCAGUUGGGAGAGCGUUAGACUGAAGAUCUAAAGGUCCCUGGUUCAAUCCCGGGUUUCGGCACCA |
| Secondary structure: | (((((((..((((........)))).(((((.......))))).....(((((.......)))))))))))).... |
| Homology model or structure extracted from PDB: |
Model Download (by Moderna) Download (by RNA Composer) (last update Sept. 6, 2019) |
| Prepared by: | Database creators |
| Version: | 1 (Sept. 6, 2019), created: May 30, 2019, modified: June 29, 2026 |
| Folding free energy [kcal/mol]: | -22.00 |
| Pre-aligned sequence: Pre-aligned secondary structure: |
-GCCGA;AUAGCUCAGUU-GGG--AGAGCGUUAGACUGAAGAUCUAAAG-------------------GNCCCUGGUUCHAUCCCGGGUUUCGGCACCA .(((((((..((((...........)))).(((((.......)))))........................(((((.......)))))))))))).... |
| Publications: |
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| Comments: | Sequence obtained from hydro-tRNAseq; modified nucleosides were not determined by MS, only predicted by mismatches frequency; relative abundance among tRNAPhe in HEK293 cells: 16.4% |
Aminoacylation
| Name | Value |
|---|---|
| Positive identity elements regulating aminoacylation: | A73; G34; A35; A36; additional core/anticodon branch determinants |
| Negative identity elements antideterminants of aminoacylation: | NA |
| Citation: | Nazarenko,I.A., Peterson,E.T., Zakharova,O.D., Lavrik,O.I. and Uhlenbeck,O.C. (1992) Recognition nucleotides for human phenylalanyl-tRNA synthetase. Nucleic Acids Res., 20, 475–478. |
| DOI: | 10.1093/nar/20.3.475 |
| PMID: | 1741281 |
Secondary structure
Tertiary structure
Model based on: