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tdbR00000821

NameValue
Coding AA: Trp
Anticodon sequence: CCA
Organism: Homo sapiens NCBI:txid9606
RNA type: cytoplasmic
Sequence: GGCCUCGUGGCGCAACGGUAGCGCGUCUGACUCCAGAUCAGAAGGUUGCGUGUUCAAAUCACGUCGGGGUCACCA
Unmodified sequence: GGCCUCGUGGCGCAACGGUAGCGCGUCUGACUCCAGAUCAGAAGGUUGCGUGUUCAAAUCACGUCGGGGUCACCA
Secondary structure: (((((((..((((.......)))).(((((.......))))).....(((((.......))))))))))))....
Homology model or
structure extracted from PDB:
Model Download (by RNA Composer) (last update July 2, 2025)
Prepared by: Database creators
Version: 1 (Sept. 6, 2019), created: May 30, 2019, modified: June 29, 2026
Folding free energy [kcal/mol]: -24.50
Pre-aligned sequence:
Pre-aligned secondary structure:
-GGCCUCGUGGCGCAAC--GGU--AGCGCGUCUGACUCCAGAUCAGAAG-------------------GUUGCGUGUUCAAAUCACGUCGGGGUCACCA
.(((((((..((((...........)))).(((((.......)))))........................(((((.......))))))))))))....
Publications:
  • Characterizing Expression and Processing of Precursor and Mature Human tRNAs by Hydro-tRNAseq and PAR-CLIP.
    Tasos Gogakos, Miguel Brown, Aitor Garzia, Cindy Meyer, Markus Hafner, Thomas Tuschl
    Cell reports
    volume: 20 issue: 6 date: Aug. 8, 2017 PUBMED ID: 28793268 DOI: 10.1016/j.celrep.2017.07.029
Comments: Sequence obtained from hydro-tRNAseq; modified nucleosides were not determined by MS, only predicted by mismatches frequency; relative abundance among tRNATrp in HEK293 cells:12.0%

Aminoacylation

NameValue
Positive identity elements regulating aminoacylation: A73; G1-C72; U5-G68/G5-C68 context; C34; C35; A36
Negative identity elements antideterminants of aminoacylation: NA
Citation: Xu,F., Chen,X., Xin,L., Chen,L., Jin,Y. and Wang,D. (2001) Species-specific differences in the operational RNA code for aminoacylation of tRNATrp. Nucleic Acids Res., 29, 4125–4133.
DOI: 10.1093/nar/29.20.4125
PMID: 11600701

Secondary structure

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Tertiary structure

Model based on:
RNA Composer