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Ile-UAU, metastatic breast cancer

Gene Ile-UAU
Disease metastatic breast cancer
Description promotes metastatic colonization in mouse xenograft models
tRNAs tdbR00000688, tdbR00000689
Publications
  • Two isoleucyl tRNAs that decode synonymous codons divergently regulate breast cancer metastatic growth by controlling translation of proliferation-regulating genes.
    Lisa B Earnest-Noble, Dennis Hsu, Siyu Chen, Hosseinali Asgharian, Mandayam Nandan, Maria C Passarelli, Hani Goodarzi, Sohail F Tavazoie
    Nature cancer
    volume: 3 issue: 12 epub: Dec. 12, 2022 PUBMED ID: 36510010 DOI: 10.1038/s43018-022-00469-9