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tdbR00000510

NameValue
Coding AA: Ini
Anticodon sequence: CAU
Organism: Escherichia coli NCBI:txid562
RNA type: cytoplasmic
Sequence: CGCGGGG4GGAGCAGCCUGGDAGCUCGUCGGGBUCAUAACCCGAAGAUCGUCGGTPCAAAUCCGGCCCCCGCAACCA
Unmodified sequence: CGCGGGGUGGAGCAGCCUGGUAGCUCGUCGGGCUCAUAACCCGAAGAUCGUCGGUUCAAAUCCGGCCCCCGCAACCA
Secondary structure: .((((((..((((.........)))).(((((.......))))).....(((((.......))))))))))).....
Homology model or
structure extracted from PDB:		 Model Download (by RNA Composer) (last update July 2, 2025)
Prepared by: Database creators
Version: 3 (June 29, 2026), created: June 29, 2026, modified: Aug. 17, 2026
Folding free energy [kcal/mol]: -30.30
Pre-aligned sequence:
Pre-aligned secondary structure:		 -CGCGGGG4GGAGCAGCCUGGD--AGCUCGUCGGGBUCAUAACCCGAAG-------------------AUCGUCGGTPCAAAUCCGGCCCCCGCAACCA
..((((((..((((...........)))).(((((.......)))))........................(((((.......))))))))))).....
Publications:
  • Separation and comparison of primary structures of three formylmethionine tRNAs from E. coli K-12 MO.
    B Z Egan, J F Weiss, A D Kelmers
    Biochemical and biophysical research communications
    volume: 55 issue: 2 date: Nov. 16, 1973 PUBMED ID: 4358398
  • Site-Specific Profiling of 4-Thiouridine Across Transfer RNA Genes in Escherichia coli
    Praneeth Bommisetti, Vahe Bandarian
    ACS omega
    volume: 7 issue: 5 date: Feb. 8, 2022 epub: Jan. 27, 2022 PUBMED ID: 35155896 DOI: 10.1021/acsomega.1c05071
Previous entry: tdbR00000510 (Aug. 17, 2026, 11:33 a.m.)

Aminoacylation

NameValue
Positive identity elements regulating aminoacylation: Initiator Met identity: CAU anticodon C34-A35-U36; initiator-specific acceptor/anticodon-loop context including C32/U33/A37 and formylation-related elements
Negative identity elements antideterminants of aminoacylation: NA
Citation: Pak,M., Pallanck,L. and Schulman,L.H. (1992) Conversion of a methionine initiator tRNA into a tryptophan-inserting elongator tRNA in vivo. Biochemistry, 31, 3303–3309.
DOI: 10.1021/bi00128a001
PMID: 1554714

Secondary structure

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Tertiary structure

Model based on:
RNA Composer