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Leu-CAG; Leu-UAG; Leu-AAG, breast cancer

Gene Leu-CAG; Leu-UAG; Leu-AAG
Disease breast cancer
Description reduced translation of Leu-enriched transcripts, including growth suppressing genes like EMP3 and GT5
tRNAs tdbR00000708, tdbR00000709, tdbR00000711, tdbR00000716, tdbR00000717, tdbR00000718
Publications
  • Leucyl-tRNA synthetase is a tumour suppressor in breast cancer and regulates codon-dependent translation dynamics.
    Maria C Passarelli, Alexandra M Pinzaru, Hosseinali Asgharian, Maria V Liberti, Søren Heissel, Henrik Molina, Hani Goodarzi, Sohail F Tavazoie
    Nature cell biology
    volume: 24 issue: 3 epub: March 14, 2022 PUBMED ID: 35288656 DOI: 10.1038/s41556-022-00856-5